The present invention relates to a method for anti-skin aging, especially for anti-skin photo-aging, by using a caffeamide derivative and/or a pharmaceutically acceptable salt thereof. In particular, the method of the present invention is for anti-oxidation, inhibiting the activity and/or expression of matrix metalloproteinase (MMP), inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), promoting the expression of collagen, inhibiting the activity and/or expression of tyrosinase, inhibiting the expression of tyrosinase related protein-1 and/or tyrosinase related protein-2, and/or absorbing ultraviolet (UV) rays with a wavelength ranging from 210 nm to 400 nm.