Age-associated degradation of proteins, search for defects that decrease efficiency of chaperon-dependent autophagy

Place of work — Department
of Developmental and
Molecular Biology, Albert
Einstein College of Medicine, USA
Contacts — Ullmann
Building Room
611D, 1300 Morris Park Av, Bronx, NY 10461.
(718) 430 2689
amuervo@aecom.yu.edu
http://www.einstein.yu.edu/
cuervo/
Publications — Restoration of chaperone-mediated autophagy in aging
liver improves cellular mainte-
nance and hepatic function. Cong Zhang, АМ Cuervo Nat
Med. 2008 Sep; 14(9): 959–965. doi:10.1038/nm.1851.
Autophagy and aging: keeping that old broom working.
Cuervo A. M. Trends Genet. T 2008
Dec;24(12):604–12.
Protein
Homeostasis and aging: taking care of proteins from the cradle to the grave.
Morimoto,
Cuervo J Gerontol A Biol Sci Med Sci. 2009; 64A: 167–170