As the population ages and rates of chronic disease rise, an increasing number of people are taking multiple pills for several conditions, often at different times throughout the day. Taking the right pill at the right time can be a hassle and potentially dangerous if a mistake is made.
Metformin is the first-line drug that can lower blood sugar levels in type 2 diabetes patients. One third of patients do not respond to metformin treatment and 5 per cent experience serious side effects, which is the reason many choose to stop medicating. Researchers at Lund University in Sweden have now identified biomarkers that can show in advance how the patient will respond to metformin treatment via a simple blood test.
Research from the Texas A&M College of Engineering could lead to new approaches to treating viruses and cancers.
Bioengineers at EPFL have created miniature intestines in a dish that match up anatomically and functionally to the real thing better than any other lab-grown tissue models. The biological complexity and longevity of the new organoid technology is an important step towards enabling drug testing, personalized medicine, and perhaps, one day, transplantations.