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Carbonyl reductases and their role in metabolism of different endogenous compounds and xenobiotics

Place of work — Institute of
Toxicology and Pharmacology
for Natural Scientists,
Christian-Albrechts-
University, Germany
Contacts — Brunswiker Str. 10, 24105,
Kiel, Germany.
+49 (431) 597–3540
maser@toxi.uni-kiel.de
http://www.uni-kiel.de/ps/
cgi-bin/exp.php?eid=82
Publications — Enzymology and molecular biology of carbonyl metabolism.
Introduction. Weiner H., Duester
G., Maser E., Plapp B. Chem Biol Interact. 2009 Mar
16;178(1–3):1.
Carbonyl reductase 1 is a predominant doxorubicin
reductase in the human liver.
Kassner N., Huse K., Martin H.J., Gödtel-Armbrust U.,
Metzger A., Meineke I., Brock-
möller J., Klein K., Zanger U.M., Maser E., Wojnowski L.
Drug Metab Dispos. 2008 Oct;36(10):2113–20.
Carbonyl
reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain
dehydro-genase/reductase superfamily. Hoffmann F., Maser E. Drug
Metab Rev. 2007;39(1):87–144.