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Changes of protein conformation associated with epigenetic heredity, phenotype changes, evolutionary process and neurodegenerative diseases

Place of work — Whitehead Institute for
Biomedical Research, USA
Contacts — 9, Cambridge Center
Cambridge, MA 02142 USA
(617) 258–5184
lindquist_admin@wi.mit.edu
Publications — Inhibiting the transcription factor HSF1 as an
anticancer strategy. Whitesell L, Lindquist S.
Expert Opin Ther Targets. 2009 Apr;13(4):469–78. Review.
Harnessing Hsp90 function as a powerful, broadly
effective therapeutic strategy for fungal
infectious disease. Cowen LE, Singh SD, Köhler JR,
Collins C, Zaas AK, Schell WA, Aziz
H, Mylonakis E, Perfect JR, Whitesell L, Lindquist S.
Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2818–23.
Heat shock factor 1 regulates lifespan as distinct from
disease onset in prion disease. Steele
AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King
OD, Raymond GJ, Aguzzi A, Lindquist S. Proc
Natl Acad Sci U S A. 2008 Sep 9;105(36):13626–31.