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Genetic and epigenetic mechanisms underlying colon cancer

Place of work — Department of Environmental
and Molecular
Toxicology, Linus Pauling
Institute, Oregon State
University, USA
Contacts — 503 Weniger Hall, Corvallis,
OR 97331–6512
(541) 737–5086
rod.dashwood@oregonstate.
edu
Publications — Dietary agents as histone deacetylase inhibitors:
sulforaphane and structurally-related isothio-
cyanates. Dashwood RH and Ho E. Nutr Rev. 2008; 66,
S36-S38.
Global histone H4 acetylation and HDAC2 expression in
colon adenoma and carcinoma.
AshktorabH, Belgrave H, Hosseinkhah F, Brim H, Nouraie
M, Takkikto M, Hewitt S, Lee EL, Dashwood RH and Smoot D. Digest Disease Sci. 2009; 54, 2109–2117.
Modulation of histone deacetylase activity by dietary
isothiocyanates and allyl sulfides: studies
with sulforaphane and garlic organosulfur compounds.
Nian H, Delage B, Ho E and Dash- wood RH. Environ Mol Mutagen. 2009; 50,
213–221.