Influence of carotenoids and retinoids on molecular and signaling pathways in cancer of lung, liver, colon, etc.

Place of work — Nutrition and Cancer
Biology Laboratory, Human
Nutrition Research
Center on Aging at Tufts
University, USA
Contacts — 711 Washington Street, Boston, MA 02111–1524,
(617) 556–3130
xiang-dong.wang@tufts.edu
Publications — Increased apoptosis in high-fat diet-induced
nonalcoholic steatohepatitis in rats is associated
with c-Jun NH2-terminal kinase activation and elevated
proapoptotic Bax. Wang Y, Ausman LM, Russell RM, Greenberg AS, Wang XD. J Nutr. 2008
Oct;138(10):1866–1871.
Apo-10'-lycopenoic acid induces Nrf2-mediated expression
of phase II detoxification and antioxidant enzymes in human bronchial epithelial cells.
Lian F, and Wang X-D. International Journal of Cancer. 2008;123:1262–1268.
Lycopene metabolites, apo-10'-lycopenoic acid, inhibits
the growth of lung cancer cells in vitro and suppresses lung carcinogenesis in A/J mice in vivo.
Lian F, Smith D, Ernst H, Russell RM, Wang X-D. Carcinogenesis. 2007;28:1567–1574.