Molecular and cellular mechanisms of hematopoietic stem cell self-renewal and process of differentiation to macrophages

Place of work — Centre
d’immunologie de
Marseille-Luminy, France
Contacts — Centre
d’immunologie de
Marseille Luminy, Case 906
13288 MARSEILLE CEDEX
09
Тел: +33 (0) 49 126–9438
sieweke@ciml.univ-mrs.fr
Publications — Aziz A, Soucie E, Sarrazin S, Sieweke MH. MafB/c-Maf
deficiency enables self-renewal of dif-
ferentiated functional macrophages. Science.
326(5954):867–71, 2009
SUMO modification regulates MafB-driven macrophage
differentiation by enabling Myb-
dependent transcriptional repression. Tillmanns S, Otto
C, Jaffray E, Du Roure C, Bakri Y,
Vanhille L, Sarrazin S, Hay RT, Sieweke MH. Mol Cell
Biol. 2007
Blood Monocytes:
Development, Heterogeneity, and Relationship with Dendritic Cells. Auffray
C, Sieweke MH, Geissmann F. Annu Rev Immunol. 2009