Process of amyloid fibril formation from “normal” proteins on molecular level

Place of work — Department
of Molecular Biology and
Biotechnology, Sheffield
Uviversity, UK
Contacts — Firth Court, Western Bank, Sheffield S10 2TN, United Kingdom +44 (1) 14 222–2761 Staniforth@sheffield.ac.uk
Publications — A method for the reversible trapping of proteins in non-native conformations. Milanesi L, Jelinska C, Hunter CA, Hounslow AM, Staniforth RA, Waltho JP. Biochemistry. 2008 Dec 23;47(51):13620–34.
Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein. Morgan GJ, Giannini S, Hounslow AM, Craven CJ, Zerovnik E, Turk V, Waltho JP, Staniforth RA. J Mol Biol. 2008 Jan 11;375(2):487–98.
Essential role of proline isomerization in stefin B tetramer formation. Jenko Kokalj S, Guncar G, Stern I, Morgan G, Rabzelj S, Kenig M, Staniforth RA, Waltho JP, Zerovnik E, Turk D. J Mol Biol. 2007 Mar 9;366(5):1569–79.