Role of NFкB factor in stem cell proliferation

Place of work — Department of Surgery,
University of Indiana, USA
Contacts — 545 Barnhill Drive, Emerson Hall 203, Indianapolis, IN 46202, USA (317) 274–5771 dmeldrum@iupui.edu http://www.ctsnet.org/home/dmeldrum
Publications — Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism. Crisostomo PR, Wang Y, Markel TA, Wang M, Lahm T, Meldrum DR. Am J Physiol Cell Physiol. 2008 294(3):C675-82. Epub 2008 Jan 30.
Differential IL-6 and VEGF secretion in adult and neonatal mesenchymal stem cells: role of NFkB. Novotny NM, Markel TA, Crisostomo PR, Meldrum DR. Cytokine. 2008 Aug;43(2):215–9. Epub 2008 Jul 14.
Proinflammatory cytokine effects on mesenchymal stem cell therapy for the ischemic heart. Abarbanell AM, Coffey AC, Fehrenbacher JW, Beckman DJ, Herrmann JL, Weil B, Meldrum DR. Ann Thorac Surg. 2009 Sep;88(3):1036–43.