Treatment with protein interleukin-7 revs up T cell immunotherapy, mouse study shows
Using advanced microscopy techniques, researchers at Karolinska Institutet and Stockholm University have visualized in unprecedented detail the machinery that the cells’ powerhouses, the mitochondria, use to form their proteins. The results, which are published in Nature, raise hopes of more specific antibiotics and new cancer drugs in the future.
In a novel experiment, a woman with advanced pancreatic cancer saw her tumors dramatically shrink after researchers in Oregon turbocharged her own immune cells, highlighting a possible new way to someday treat a variety of cancers.
The approach, studied in mice, overcomes the blood brain barrier and breaks the shield tumors build against the immune response.
For decades, paleontologists have debated whether dinosaurs were warm-blooded, like modern mammals and birds, or cold-blooded, like modern reptiles. Knowing whether dinosaurs were warm- or cold-blooded could give us hints about how active they were and what their everyday lives were like, but the methods to determine their warm- or cold-bloodedness-- how quickly their metabolisms could turn oxygen into energy-- were inconclusive.