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Taking Out the Trash is Essential for Brain Health

A research team at Tokyo Medical and Dental University (TMDU) find that Wipi3, a protein involved in cellular waste disposal, is crucial for neuronal health
research
Researchers Improve Neuronal Reprogramming by Manipulating Mitochondria

The replacement of lost neurons is a holy grail for neuroscience. A new promising approach is the conversion of glial cells into new neurons. Improving the efficiency of this conversion or reprogramming after brain injury is an important step towards developing reliable regenerative medicine therapies. Researchers at Helmholtz Zentrum München and Ludwig Maximilians University Munich (LMU) have identified a hurdle towards an efficient conversion: the cell metabolism. By expressing neuron-enriched mitochondrial proteins at an early stage of the direct reprogramming process, the researchers achieved a four times higher conversion rate and simultaneously increased the speed of reprogramming.
research
Rensselaer-Developed Algorithm Accurately Predicts COVID-19 Patient Outcomes

AI tool could help clinicians provide more effective COVID-19 intervention
COVID-19
Researchers use cutting edge technology to bioprint mini-kidneys

Researchers have used cutting edge technology to bioprint miniature human kidneys in the lab, paving the way for new treatments for kidney failure and possibly lab-grown transplants.
bioprinting technology medical and health
Sestrin makes fruit flies live longer

Researchers identify positive effector behind reduced food intake
research
Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

TAU breakthrough may increase life expectancy in brain and ovarian cancers
research CRISPR
Engineered immune cells elicit broad response to HIV in mice, offering hope for vaccine or functional cure

Scientists developed an approach that successfully generates antibodies against numerous strains of the fast-evolving human immunodeficiency virus.
research
Small molecule, big potential for treating prostate cancer

MIT researchers identify a molecule that could target advanced prostate cancer as well as a variety of other cancers.
research cancer
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