In an unprecedented atlas, researchers begin to map how genes are turned on or off in different cells, a step toward better understanding the connections between genetics and disease
Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers at Lund University in Sweden have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a difference which, despite all our similarities, may explain why our brains work differently. The study is published in the journal Cell Stem Cell.
A new mechanism that stops the progression of Huntington’s disease in cells has been identified by scientists at UCL and the University of Cambridge, as part of their research groups at the UK Dementia Research Institute.
A multi-functional, small molecule can tag mutant genetic sequences inside mitochondria for removal.
A technique for labeling and retrieving DNA data files from a large pool could help make DNA data storage feasible.
Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University of Zurich has succeeded in sustainably lowering high LDL cholesterol levels in the blood of mice and macaques. This opens up the possibility of curing patients with inherited metabolic liver diseases.