The discovery of how telomeres and mitochondria communicate to promote inflammation opens new possibilities for preventing and treating cancer and other harmful consequences of aging
Using bottlebrush-shaped particles, researchers can identify and deliver synergistic combinations of cancer drugs.
Polish scientists revealed the potential for new cancer drugs to be formulated from bioactive compounds found in plants from the genus Solanum, like potatoes and aubergines.
A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with neuroendocrine cancers and reduced tumor size in two of those patients. It also showed some therapeutic activity against sarcomas, scientists and clinicians report in the British Journal of Cancer.
University of Saskatchewan (USask) researchers have developed a new method of killing brain cancer cells while preserving the delicate tissue around it. The technique also has a remarkable side-benefit: making chemotherapy treatment of brain cancer suddenly possible.
Liver cancer is one of the most deadly types of cancer. The team led by Prof. Michael N. Hall from the Biozentrum of the University of Basel has now uncovered how a healthy liver cell turns into a tumor cell. Comprehensive metabolic changes convert mature liver cells into immature progenitor cells. These cells proliferate rapidly and tumors develop.