Study in mice could point toward method for clearing virus from people who would otherwise depend on medication
In the 40 years since the first published reports of the syndrome known as AIDS, more than 32 million people have died from the virus that causes it, the human immunodeficiency virus (HIV). With more than 35 million people worldwide living with HIV today and nearly two million new cases each year, HIV remains a major global epidemic.
Study uncovers stem cells’ ability to restore immunity and repair gut damage caused by HIV
Research from the UNC School of Medicine lab of Jenny Ting, PhD, shows that the widely used drug metformin reduces metabolism of infected T cells to suppress HIV replication.
A recent study published in the journal Nature Medicine, led by researchers Todd Allen, PhD, a professor of Medicine at Harvard Medical School (HMS) and group leader at the Ragon Institute of MGH, MIT and Harvard, and Jim Riley, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection. The paper's first authors are Colby Maldini, a graduate student at the University of Pennsylvania and Daniel Claiborne, PhD, a research fellow at the Ragon Institute.
Most vaccines direct the adaptive immune system to fight off infections with one arm tied behind its back. A new study in monkeys untied the other arm.