Authors:
History:
In 1930s,
Example:
A study of a lifespan was made by the University of Wisconsin in 1989 — 2014. It involved nonhuman primates (rhesus monkeys) and found that caloric restriction primates were only 36.4% as likely to die from
Description:
Increasing evidence suggests that energy balance is central to both successful ageing and protection from metabolic disorders.
Energy restriction, also known as caloric restriction, is currently the only dietary intervention that is proven to increase longevity and delay the onset of
Calorie restriction, or caloric restriction (CR), is a dietary regimen that is based on low calorie intake but without malnutrition. «Low» can be defined relative to the subject’s previous intake before intentionally restricting calories, or relative to an average person of similar body type.
Even though there has been research on CR for over 70 years, the mechanism by which CR works is still not well understood. Some explanations include reduced core body temperature, reduced cellular divisions, lower metabolic rates, reduced production of free radicals, reduced DNA damage and hormesis.
Additions and Criticism:
It should be noted that
Publications:
- Spindler, Stephen R., Joseph M. Dhahbi, and Patricia L. Mote. «Protein turnover, energy metabolism, aging, and caloric restriction." Advances in cell aging and gerontology 14 (2003): 69–86.
- Ungvari, Zoltan, et al. «Mechanisms Underlying Caloric Restriction and Lifespan Regulation Implications for Vascular Aging." Circulation research 102.5 (2008): 519–528.
- Mattison, Julie A., et al. «Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study." Nature (2012).
- Willcox, Bradley J., et al. «Caloric restriction, the traditional Okinawan diet, and healthy aging." Annals of the New York Academy of Sciences 1114.1 (2007): 434–455.